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  3. UCM-05194

UCM-05194是一种选择性LPA1受体激动剂,具有改善神经性疼痛的活性。UCM-05194作为一种LPA1激动剂,在其类药理特性下表现出强效和选择性。UCM-05194促发LPA1介导的细胞效应,并导致受体的内化,从而在初级感觉神经元中实现功能失活。UCM-05194在体内模型中有效减轻疼痛感知。UCM-05194可用于进行渐进性系统疾病的研究。

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UCM-05194 Chemical Structure

UCM-05194 Chemical Structure

CAS No. : 2411412-36-5

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  • 生物活性

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生物活性

UCM-05194 is a selective LPA1 receptor agonist with activity to improve neuropathic pain. UCM-05194 is a LPA1 agonist that exhibits potent and selective properties in its pharmacologically similar properties. UCM-05194 triggers LPA1-mediated cellular effects and leads to internalization of the receptor, resulting in functional inactivation in primary sensory neurons. UCM-05194 effectively reduces pain perception in in vivo models. UCM-05194 can be used to conduct research on progressive systemic diseases[1].

分子量

465.32

Formula

C19H30BrO6P

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

UCM-05194 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
UCM-05194
目录号:
HY-167862
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