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Ursonic acid methyl ester  (Synonyms: 3-羰基-熊果酸-28-甲酯)

目录号: HY-N7623
产品使用指南

Ursonic acid methyl ester 是乌索酸 (HY-N0140) 的酯化衍生物。Ursonic acid methyl ester 对 HL-60、BGC、Bel-7402 和 Hela 细胞生长抑制的 ED50 均大于 100 µg/ml。

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Ursonic acid methyl ester Chemical Structure

Ursonic acid methyl ester Chemical Structure

CAS No. : 989-72-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ursonic acid methyl ester is an esterified derivative of Ursolic acid (HY-N0140). Ursonic acid methyl ester shows growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela with ED50 values of >100 µg/ml[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
518A2 EC50
1.24 μM
Compound: 7
Cytotoxicity against human 518A2 cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human 518A2 cells assessed as cell survival after 96 hrs by SRB assay
[PMID: 26177446]
8505C EC50
1.56 μM
Compound: 7
Cytotoxicity against human 8505C cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human 8505C cells assessed as cell survival after 96 hrs by SRB assay
[PMID: 26177446]
A549 EC50
1.64 μM
Compound: 7
Cytotoxicity against human A549 cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as cell survival after 96 hrs by SRB assay
[PMID: 26177446]
HepG2 CC50
> 400 μM
Compound: 5a
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
[PMID: 29326018]
HT-29 EC50
1.15 μM
Compound: 7
Cytotoxicity against human HT-29 cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human HT-29 cells assessed as cell survival after 96 hrs by SRB assay
[PMID: 26177446]
MCF7 EC50
1.3 μM
Compound: 7
Cytotoxicity against human MCF7 cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human MCF7 cells assessed as cell survival after 96 hrs by SRB assay
[PMID: 26177446]
NTUB1 IC50
29.57 μM
Compound: 19
Cytotoxicity against human NTUB1 cells after 72 hrs by MTT assay
Cytotoxicity against human NTUB1 cells after 72 hrs by MTT assay
[PMID: 19758808]
Vero CC50
> 400 μM
Compound: 5a
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
[PMID: 29326018]
分子量

468.71

Formula

C31H48O3

CAS 号
中文名称

3-羰基-熊果酸-28-甲酯

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Ursonic acid methyl ester 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Ursonic acid methyl ester
目录号:
HY-N7623
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