产品详情

Biological activity

•   A unique collection of 54,080 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

•   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, ETA Receptor, etc.

•   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

•   Structurally diverse.

•   Novel sp3-enriched scaffolds specifically designed as cores for GPCR Library.

•   The following molecular parameters were applied in construction of the library:

    MW = 200...550, ClogP = -1.5...5.5, TPSA ≤ 150 Å2, RotBonds ≤ 9, HBD/HBA ≤ 4/10.

•   Databases and compounds are provided by Enamine.