产品详情

Biological activity

•   A set of 5 compounds targeting lipid GPCR.

•   The collection may also be appropriate for screening at GPR3, GPR6 and GPR12 orphan receptors given some TM bundle binding site similarity and/or GPR23, GPR92 and P2Y5 given their more recent classification as additional, albeit distinct, LPA receptors.

•   The compounds have been selected using a combination of ligand-based methods using chemical fingerprints, 2D pharmacophores and 3D shape/feature matches.

•   Structurally diverse.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds can be readily followed with analogues either from stock or from new synthesis.

•   Databases and compounds are provided by Enamine.