2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. VU590 dihydrochloride

VU590 dihydrochloride 是一种有效的和中等选择性的肾外髓质钾 ROMK (Kir1.1) 抑制剂，IC50 为290 nM。VU590 对 Kir7.1 也具有抑制作用，IC50 为 8 μM。VU590 dihydrochloride 不是肾脏中 ROMK 功能的良好探针。

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VU590 dihydrochloride Chemical Structure

VU590 dihydrochloride Chemical Structure

CAS No. : 1783987-83-6

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规格 价格 是否有货 数量
5 mg ￥1620
3 - 4 周
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Other Forms of VU590 dihydrochloride:

VU590 dihydrochloride 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

VU590 dihydrochloride is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 dihydrochloride is not a good probe of ROMK function in the kidney[1][2].

IC50 & Target

IC50: 290 nM (Kir1.1), 8 μM (Kir7.1)[1]
分子量

561.46

Formula

C24H34Cl2N4O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VU590 dihydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

VU5901783987-83-6VU 590VU-590Potassium ChannelKcsAPotassium (K+) ChannelRenal outer medullary potassium channel (ROMK)Inward rectifier potassium (Kir)Diuretic targetInhibitorinhibitorinhibit

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产品名称：
VU590 dihydrochloride
目录号：
HY-110076
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