2. Metabolic Enzyme/Protease
  3. Xanthine Oxidase
  4. Xanthine oxidoreductase-IN-5

Xanthine oxidoreductase-IN-5 是一种具有口服活性的黄氨酸氧化还原酶 (XOR) 抑制剂，IC50 值为 55 nM。Xanthine oxidoreductase-IN-5 可用于研究急性高尿酸血症。

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Xanthine oxidoreductase-IN-5 Chemical Structure

Xanthine oxidoreductase-IN-5 Chemical Structure

CAS No. : 1026652-90-3

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Xanthine oxidoreductase-IN-5 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Xanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 55 nM. Xanthine oxidoreductase-IN-5 can be used for the research of acute hyperuricemia[1].

IC50 & Target

IC50: 55 nM (xanthine oxidoreductase)[1]
体内研究
(In Vivo)

Xanthine oxidoreductase-IN-5 (化合物 IIIa) (5 mg/kg; 口服给药) 在给药后 5 h 显示出降低急性高尿酸血症小鼠尿酸的作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ICR mice (18-22 g) were induced acute hyperuricemia by injection of potassium oxonate and hypoxanthine[1]
Dosage: 5 mg/kg
Administration: Suspended in 0.5% CMC-Na solution for intragastric administration
Result: Showed a uric acid-lowering effect from 5 h after administration.
分子量

323.35

Formula

C17H17N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Xanthine oxidoreductase-IN-5 相关分类

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Keywords:

Xanthine oxidoreductase-IN-51026652-90-3Xanthine OxidaseXOxanthine oxidoreductaseXORacute hyperuricemiaInhibitorinhibitorinhibit

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