2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. Z-335 sodium

Z-335 sodium 是一种口服活性的血栓素A2 (TXA2) 受体拮抗剂，其对人和豚鼠血小板的 IC50 值分别为 29.9 nM 和 32.5 nM。

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Z-335 sodium Chemical Structure

Z-335 sodium Chemical Structure

CAS No. : 146731-14-8

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Z-335 sodium 相关抗体

Top Publications Citing Use of Products

查看 Prostaglandin Receptor 亚型特异性产品:

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DP EP FP IP TXA2/TP TXB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Z-335 sodium is an orally active thromboxane a2 (TXA2) receptor antagonist, with IC50 values of 29.9 nM and 32.5 nM for human and Guinea pig platelets, respectively[1][2].

体内研究
(In Vivo)

Z-335 (0.3-3 mg/kg, p.o.) 以剂量依赖的方式抑制血栓形成。Z-335 (3 mg/kg, p.o.) 即使在 16 小时后也能显著防止血栓形成[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

401.84

Formula

C18H17ClNNaO4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Z-335 sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-335146731-14-8Z335Z 335Prostaglandin ReceptorThromboxane AArterial thrombosisCilostazolInhibitorinhibitorinhibit

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目录号：
HY-19249
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