2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Zacopride

Zacopride是一种选择性激动剂，具有增强兔心脏内向整流钾电流（IK1）的活性。Zacopride还表现出显著的抗心律失常效果，通过提高IK1来抑制心室心律失常，而不影响心房心律失常。Zacopride可以超极化静息膜电位，并以浓度依赖的方式缩短动作电位持续时间（APD）。Zacopride在1μmol/L时显著降低了化合物诱导的早期后除极（EAD）发生率。

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Zacopride Chemical Structure

Zacopride Chemical Structure

CAS No. : 90182-92-6

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Zacopride 的其他形式现货产品:

Other Forms of Zacopride:

Zacopride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Zacopride is a selective agonist with the activity of enhancing the inward rectifier potassium current (IK1) in rabbit hearts. Zacopride also exhibits significant antiarrhythmic effects, inhibiting ventricular arrhythmias by increasing IK1 without affecting atrial arrhythmias. Zacopride can hyperpolarize the resting membrane potential and shorten the action potential duration (APD) in a concentration-dependent manner. Zacopride significantly reduced the incidence of compound-induced early afterdepolarizations (EADs) at 1 μmol/L[1].

分子量

309.79

Formula

C15H20ClN3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Zacopride 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Zacopride90182-92-6Endogenous MetaboliteInhibitorinhibitorinhibit

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