1. Vitamin D Related/Nuclear Receptor
  2. Androgen Receptor
  3. Zanoterone

Zanoterone 是口服有效的雄激素受体 (AR) 的拮抗剂 (Ki=2.2 μM)。Zanoterone 阻止雄激素如睾酮和二氢睾酮 (DHT) 的结合,抑制雄激素信号通路,从而减少雄激素依赖的前列腺增生和前列腺癌的生长。

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Zanoterone Chemical Structure

Zanoterone Chemical Structure

CAS No. : 107000-34-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Zanoterone is an orally active antagonist of the androgen receptor (AR) with a Ki of 2.2 μM. Zanoterone blocks the binding of androgens such as testosterone and dihydrotestosterone (DHT), inhibiting the androgen signaling pathway, thereby reducing androgen-dependent prostate hyperplasia and prostate cancer growth[1].

分子量

416.58

Formula

C23H32N2O3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Zanoterone
目录号:
HY-105122
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