2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. ZM 253270

ZM 253270 是一种具有物种选择性的非肽类 NK-2 受体 (NK-2R) 拮抗剂。ZM 253270 竞争性抑制 [3H]NKA 与仓鼠膀胱的天然或克隆的 NK-2R 的结合 (Ki=2 nM)，但抑制 [3H]NKA 与克隆的人类 NK-2R 结合的抑制作用较弱 (降低 48 倍)。

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ZM 253270 Chemical Structure

ZM 253270 Chemical Structure

CAS No. : 169340-04-9

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ZM 253270 相关抗体

Top Publications Citing Use of Products

查看 Neurokinin Receptor 亚型特异性产品:

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NK1 NK2 NK3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ZM 253270 is a species-selective non-peptide NK-2 receptor (NK-2R) antagonist. ZM 253270 competitively inhibits the binding of [3H]NKA to native or cloned NK-2R from hamster bladder (Ki=2 nM), but has a weaker inhibitory effect (48-fold) on the binding of [3H]NKA to cloned human NK-2R[1].

IC50 & Target[1]

Hamster Bladder NK-2

2 nM (Ki)

分子量

471.94

Formula

C22H26ClN7O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ZM 253270 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZM 253270169340-04-9ZM253270ZM-253270Neurokinin ReceptorNK receptorTachykinin receptorSpecies selectionantagonisthamsterNKAnon-peptide receptorInhibitorinhibitorinhibit

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产品名称：
ZM 253270
目录号：
HY-117053
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