1. Epigenetics Metabolic Enzyme/Protease
  2. HuR MMP
  3. ZM-32

ZM-32 是人类抗原 R (HuR) 抑制剂,可下调 VEGF-A 和 MMP9 的表达,从而抑制乳腺癌肿瘤血管生成。ZM-32 在多种癌细胞系中表现出广谱抗增殖作用,并在小鼠模型中对 MDA-MB-231 表现出抗肿瘤功效。

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ZM-32 Chemical Structure

ZM-32 Chemical Structure

CAS No. : 2667585-44-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ZM-32 is an inhibitor for human antigen R (HuR), that downregulates the expression of VEGF-A and MMP9, and thus inhibits breast cancer tumor angiogenesis. ZM-32 exhibits broad-spectrum anti-proliferative effects in a variety of cancer cell lines, and exhibits antitumor efficacy against MDA-MB-231 in mouse models[1].

分子量

387.56

Formula

C24H37NO3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
ZM-32
目录号:
HY-163760
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