2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. α-Conotoxin GIC

α-Conotoxin GIC 是一种有效的选择性 α3β2 烟碱拮抗剂，其 IC50 为 1.1 nM。

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α-Conotoxin GIC Chemical Structure

α-Conotoxin GIC Chemical Structure

CAS No. : 757236-92-3

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α-Conotoxin GIC 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

α-Conotoxin GIC is a potent and selective α3β2 nicotinic antagonist with an IC50 of 1.1 nM[1].

IC50 & Target

IC50: 1.1 nM (hα3β2), 309 nM (hα4β2), 755 nM (hα3β4), >100,000 nM (hα1β1δ?)[1]
分子量

1609.79

Formula

C61H92N24O20S4
CAS 号
Sequence

Gly-Cys-Cys-Ser-His-Pro-Ala-Cys-Ala-Gly-Asn-Asn-Gln-His-Ile-Cys-NH2 (Disulfide bridge:Cys2-Cys8;Cys3-Cys16)
Sequence Shortening

GCCSHPACAGNNQHIC-NH2 (Disulfide bridge:Cys2-Cys8;Cys3-Cys16)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

α-Conotoxin GIC 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Conotoxin GIC757236-92-3nAChRNicotinic acetylcholine receptorsConus geographusXenopus oocytesInhibitorinhibitorinhibit

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产品名称：
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目录号：
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