2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. α-Conotoxin MrIC

α-Conotoxin MrIC 是一种 α7nAChR 偏向激动剂。α-Conotoxin MrIC 只激活 II 型正变构调节剂 (包括 PNU120596) 调节的 α7nAChR。α-Conotoxin MrIC 可用于神经系统疾病的研究，也可探测 α7nAChR 的药理学特性。

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Custom Peptide Synthesis

α-Conotoxin MrIC Chemical Structure

α-Conotoxin MrIC Chemical Structure

CAS No. : 1417816-41-1

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α-Conotoxin MrIC 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

α-Conotoxin MrIC is an α7nAChR biased agonist. α-Conotoxin MrIC exclusively activates α7nAChR regulated by type II positive allosteric modulators, including PNU120596. α-Conotoxin MrIC can be used to study neurological diseases and also to probe the pharmacological properties of α7nAChR[1].

IC50 & Target

α7nAChR[1].
分子量

1835.07

Formula

C74H111N23O24S4
CAS 号
Sequence

Pro-Glu-Cys-Cys-Thr-His-Pro-Ala-Cys-His-Val-Ser-Asn-Pro-Glu-Leu-Cys-NH2 (Disulfide bridge:Cys3-Cys9, Cys4-Cys17)
Sequence Shortening

PECCTHPACHVSNPELC-NH2 (Disulfide bridge:Cys3-Cys9, Cys4-Cys17)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

α-Conotoxin MrIC 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Conotoxin MrIC1417816-41-1nAChRNicotinic acetylcholine receptorsSH-SY5YPNU120596Inhibitorinhibitorinhibit

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