1. Immunology/Inflammation
  2. Interleukin Related
  3. α-Galactosylceramide

α-Galactosylceramide  (Synonyms: α-GalCer; KRN7000)

目录号: HY-102022G
产品使用指南 技术支持

α-Galactosylceramide (α-GalCer) (GMP) 是一种 GMP 级别的 α-Galactosylceramide (HY-102022)。GMP 级别小分子可用作细胞疗法中的辅助试剂。α-Galactosylceramide (GMP) 可在体外激活 iNKT 细胞,伴随 IL-4IFN-γ 的快速分泌、细胞表面 TCR 瞬时下调、克隆扩增和稳态收缩。α-Galactosylceramide 是一种非常有效的 NKT 细胞激动剂,可有效结合 CD1d

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α-Galactosylceramide Chemical Structure

α-Galactosylceramide Chemical Structure

CAS No. : 158021-47-7

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  • 生物活性

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生物活性

α-Galactosylceramide (α-GalCer) (GMP) is a GMP-grade α-Galactosylceramide (HY-102022). Small molecules of GMP grade can be used as adjuvant reagents in cell therapy. α-Galactosylceramide (GMP) can activate iNKT cells in vitro, characterized by rapid secretion of IL-4 and IFN-γ, transient downregulation of cell-surface TCR, clonal expansion and homeostatic contraction. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d[1].

分子量

858.34

Formula

C50H99NO9

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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α-Galactosylceramide
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HY-102022G
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