α-Glucosidase, Yeast  (Synonyms: α-葡萄糖苷酶，来源于酵母; α-D-Glucosidase, Yeast)

α-Glucosidase, Yeast (α-D-Glucosidase, Yeast), a carbohydrate hydrolyzing enzyme, catalyzes the liberation of α-glucose from the non-reducing end of the substrate. α-Glucosidase can facilitate the absorption of glucose by the small intestine. Inhibition of α-Glucosidase is an effective management of non-insulin-dependent diabetes mellitus (NIDDM)^[1][2].

产品信息
分子量：68.5 kDa
等电点（pI）：5.9
最适 pH: 6.5-7.5
最适反应温度：37℃
pH 稳定性：6.0-8.5（25℃，24小时）
抑制剂：组氨酸、胺（Tris）、金属离子（Hg²⁺、Cu²⁺、Ag⁺、Pb²⁺、Fe²⁺ 和 Zn²⁺）、碘乙酸盐、4-氯汞苯甲酸盐。

使用说明
可 1 mg/mL 溶于水，根据单次使用量分装后于 -20℃ 冻存，避免反复冻融，最长可保存 1个月。也可根据具体实验参考文献 buffer 进行溶解。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

α-Glucosidase, Yeast 是存在于小肠上皮细胞中的一种膜结合酶，其通过催化寡糖水解裂解成可吸收的来促进小肠对葡萄糖的吸收。抑制 α-Glucosidase 可减缓碳水化合物餐后血糖的升高^[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

9001-42-7

固体

White to off-white

Α-葡糖苷酶，来源于酵母；α-葡萄糖苷酶，来源于酵母；A-葡萄糖苷酶，来源于酵母

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Kumar S, et, al. α-glucosidase inhibitors from plants: A natural approach to treat diabetes. Pharmacogn Rev. 2011 Jan;5(9):19-29.  [Content Brief]

  [2]. Laar FA, et, al. Alpha-glucosidase inhibitors for patients with type 2 diabetes: results from a Cochrane systematic review and meta-analysis. Diabetes Care. 2005 Jan;28(1):154-63.  [Content Brief]