2. Anti-infection
  3. SARS-CoV
  4. αGalCer-RBD

αGalCer-RBD 是一种佐剂脂蛋白结合物。αGalCer-RBD 可诱导对 SARS-CoV-2 及其变异毒株的有效免疫。αGalCer-RBD 结合物诱导 RBD 特异性、产生细胞因子的T细胞发育。αGalCer-RBD 有望成为一种有效的 COVID-19 疫苗候选化合物。α-Galactosylceramide (αGalCer) 是一种有效的不变自然杀伤T细胞 (iNKT) 激动剂。

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αGalCer-RBD Chemical Structure

αGalCer-RBD Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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αGalCer-RBD 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

αGalCer-RBD is a self-adjuvanting lipoprotein conjugate. αGalCer-RBD induces potent immunity against SARS-CoV-2 and its variants of concern. αGalCer-RBD conjugate induces RBD-specific, cytokine-producing T cell development. αGalCer-RBD has great potential to be an effective COVID-19 vaccine candidate. α-Galactosylceramide (αGalCer) is a potent invariant natural killer T cell (iNKT) agonist[1]. RBD: receptor-binding domain

体外研究
(In Vitro)

The first time conjugates the iNKT cell agonist on the protein antigen, and the resulting αGalCer-RBD conjugate anchored on liposomes biomimicking the virus capsid structure remarkably enhances the protective immune response against SARS-CoV-2[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

αGalCer-RBD 相关抗体:
体内研究
(In Vivo)

αGalCer-RBD enhances the immune efficacy of the adjuvant and produces significantly stronger humoral responses and cellular responses in mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1119.60

Formula

C60H118N4O14
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

αGalCer-RBD 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

αGalCer-RBDSARS-CoVSARS coronavirusRBDimmune efficacycellular responsesiNKT cellliposomescytokineSARS-CoV-2COVID-19Inhibitorinhibitorinhibit

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