2. Stem Cell/Wnt Apoptosis
  3. β-catenin Wnt c-Myc
  4. β-catenin-IN-8

β-catenin-IN-8 (Compound 25) 是一种 β-catenin 抑制剂。β-catenin-IN-8 抑制 β-catenin 和 c-Myc 蛋白水平，并抑制 Wnt 靶基因水平 (Fgf20 和 Sall4)。β-catenin-IN-8 具有结直肠癌抗癌活性，并具有代谢稳定性。

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β-catenin-IN-8 Chemical Structure

β-catenin-IN-8 Chemical Structure

CAS No. : 259130-14-8

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β-catenin-IN-8 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

β-catenin-IN-8 (Compound 25) is a β-catenin inhibitor. β-catenin-IN-8 inhibits β-catenin and c-Myc protein levels, and inhibits Wnt-target genes level (Fgf20 and Sall4). β-catenin-IN-8 has colorectal cancer anticancer activities, and has metabolic stability[1].

体外研究
(In Vitro)

β-catenin-IN-8 inhibits the growth of SW480 and HCT116 cancer cells with IC50s of 2 and 0.12 μM respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

β-catenin-IN-8 相关抗体:
分子量

333.79

Formula

C15H12ClN3O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

β-catenin-IN-8 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-catenin-IN-8259130-14-8β-cateninWntc-MycBeta cateninMycCRCanticancerInhibitorinhibitorinhibit

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