2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. γ-Kainylglutamic acid

γ-Kainylglutamic acid  (Synonyms: γ-Kainic acid-glutamic acid)

目录号: HY-118758
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摩尔计算器

γ-Kainylglutamic acid (γ-Kainic acid-glutamic acid)，一种源自凯氨酸和 L-谷氨酸的二肽，是一种氨基酸引起的神经兴奋的选择性拮抗剂，具有抗惊厥特性。γ-Kainylglutamic acid 抑制了由神经刺激剂 N-甲基-D-天冬氨酸在脑切片中诱导的 Na+ 通道的刺激。γ-Kainylglutamic acid 在保护小鼠免受百草枯引起的惊厥方面也有效，EC50 值为 0.17 μmol。

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γ-Kainylglutamic acid Chemical Structure

γ-Kainylglutamic acid Chemical Structure

CAS No. : 98394-38-8

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γ-Kainylglutamic acid 相关抗体

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  • 生物活性

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生物活性

γ-Kainylglutamic acid (γ-Kainic acid-glutamic acid), a dipeptide derived from kainic and L-Glutamic acids, is a selective antagonist of amino acid induced neuroexcitation with anticonvulsant properties. γ-Kainylglutamic acid inhibits the stimulation of Na+ fluxes induced in brain slices by the neuroexcitant N-methyl-D-aspartic acid. γ-Kainylglutamic acid is also effective in protecting mice from picrotoxin-induced convulsions with an EC50 value of 0.17 μmol[1].

分子量

342.34

Formula

C15H22N2O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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参考文献

γ-Kainylglutamic acid 相关分类

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Keywords:

γ-Kainylglutamic acid98394-38-8γ-Kainic acid-glutamic acidSodium ChannelNa channelsNa+ channelsdipeptideneuroexcitationanticonvulsantNa+ fluxesconvulsionsInhibitorinhibitorinhibit

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