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  4. 1,10-Decanediol

1,10-Decanediol  (Synonyms: 1,10-癸二醇)

目录号: HY-W016773 纯度: 99.93%
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1,10-Decanediol 是一种二醇类化合物，可用于与 α-酮戊二酸 (aKG) 反应，生成二醇基聚合微粒 (称为 paKG MPs)，来持续释放 aKG，从而促进免疫抑制调节。此外，paKG MPs 可与树突状细胞 (DCs) 结合，来减少其体外的糖酵解和线粒体呼吸，这些代谢变化会导致 DCs 中 MHC-II 和 CD86 表达调节，并改变体外调节性 T 细胞 (Tregs) 以及辅助性 T 细胞 1/2/17 型的频率。1,10-Decanediol 可用于免疫代谢领域领域的研究。

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1,10-Decanediol Chemical Structure

1,10-Decanediol Chemical Structure

CAS No. : 112-47-0

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规格 价格 是否有货
100 g ￥300
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Other Forms of 1,10-Decanediol:

1,10-Decanediol 相关抗体

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  • 生物活性

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生物活性

1,10-Decanediol is a diol compound that can react with α-ketoglutarate (aKG) to generate polymeric microparticles (termed paKG MPs) for the sustained release of aKG, thereby promoting immunosuppressive regulation. Additionally, paKG MPs can bind to dendritic cells (DCs), reducing their glycolysis and mitochondrial respiration in vitro. These metabolic changes lead to the modulation of MHC-II and CD86 expression in DCs and alter the frequency of regulatory T cells (Tregs) as well as T-helper type 1/2/17 cells in vitro. 1,10-Decanediol can be used in research within the field of immunometabolism[1].

分子量

174.28

Formula

C10H22O2
CAS 号
性状

固体

颜色

White to off-white

中文名称

1,10-癸二醇
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料

纯度: 99.93%

COA (276 KB) HNMR (115 KB) GC (204 KB)

产品使用指南 (1538 KB)
参考文献

1,10-Decanediol 相关分类

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Keywords:

1,10-Decanediol112-47-01,10-癸二醇OthersInhibitorinhibitorinhibit

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