2. 一站式药筛
  3. 化合物库
  4. RO5 类药天然产物库
RO5 类药天然产物库 - RO5 Drug-like Natural Product Library

Cat. No.: HY-L200

天然产物是自然界中产生的，来自于任何生物体的小分子化合物，其中包括初级代谢物及次级代谢物。天然产物具有潜在的生物活性，可以作为药物发现的先导化合物。数千年来，大自然一直是药物的来源，大量现代药物从自然界中分离得到，许多是基于它们在传统医学中的用途。随着化合物靶点的开发，对筛选化合物多样性的需求越来越大。通过对自然界生物多样性的持续研究，其中许多生物多样性仍有待开发，天然产物将在满足这一需求方面发挥关键作用。类药五原则（Lipinski rule of 5）是用来描述一个分子类似药物的性质，遵守5法则的分子具有更高的药物潜力。MCE 在已有天然产物库的基础之上，筛选出了符合类药五原则的分子，使得药物筛选的效率更高。

MCE收录了 2,717 个符合 RO5 类性的药物天然产物，是药物发现的重要工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE RO5 类药天然产物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，2,673 个产品以 10 mM 浓度提供，44 个产品以 2 mM 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料

活性描述 & 特点

Biological Activity

•   A unique collection of 2,717 RO5 drug-like natural product for high throughput screening (HTS) and high content screening (HCS).

The compounds in the library contain Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes.

•   A useful tool for the discovery of compounds for drug screening.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 2,717 RO5 drug-like natural products supplied as pre-dissolved solutions or solid.
Solution: 2,673 compounds supplied in 10 mM solution, 44 compounds supplied in 2 mM solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    RO5 Drug-like Natural Product Library
    目录号：
    HY-L200
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