2. 天然产物
  3. 植物 疾病研究领域 萜类
  4. 豆科 炎症/免疫 唇形科 二萜
  5. 雨树
  6. 1,2-Dihydrotanshinone

1,2-Dihydrotanshinone  (Synonyms: 1,2-Dihydrotanshinquinone)

目录号: HY-122970
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摩尔计算器

1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) 是一种松香烷二萜。1,2-Dihydrotanshinone 抑制 (CUG) n-RNA 和剪接因子 muscleblind-like 1 之间形成的致病复合物的形成。1,2-Dihydrotanshinone 可用于强直性肌营养不良 1 型的研究。

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1,2-Dihydrotanshinone Chemical Structure

1,2-Dihydrotanshinone Chemical Structure

CAS No. : 77769-21-2

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规格 价格 是否有货 数量
1 mg ￥2380
1 - 2 周
5 mg 现货 1 - 2 周
10 mg   询价  
50 mg   询价  

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1,2-Dihydrotanshinone 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) is an abietane diterpene. 1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1). 1,2-Dihydrotanshinone can be used for the research of myotonic dystrophy type 1[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MIA PaCa-2 IC50
5.6 μM
Compound: 16
Cytotoxicity against human MIAPaCa2 cells after 24 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells after 24 hrs by MTT assay
[PMID: 21775156]
体外研究
(In Vitro)

1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1) (≥50% inhibition at 100 µg/mL)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1,2-Dihydrotanshinone 相关抗体:
分子量

278.30

Formula

C18H14O3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

1,2-Dihydrotanshinone 相关分类

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Keywords:

1,2-Dihydrotanshinone77769-21-21,2-DihydrotanshinquinoneOthersabietanediterpenemyotonicdystrophyInhibitorinhibitorinhibit

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