1. 天然产物
  2. 疾病研究领域 内源性代谢物 其他类
  3. 代谢疾病
  4. 1-Palmitoyl-sn-glycerol 3-phosphate

1-Palmitoyl-sn-glycerol 3-phosphate  (Synonyms: 1-P-GPA)

目录号: HY-126967A 纯度: ≥99.0%
COA 产品使用指南

1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) 是一种内源性代谢物。1-Palmitoyl-sn-glycerol 3-phosphate 可用于非酒精性脂肪性肝病的研究。

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1-Palmitoyl-sn-glycerol 3-phosphate Chemical Structure

1-Palmitoyl-sn-glycerol 3-phosphate Chemical Structure

CAS No. : 7220-34-0

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规格 价格 是否有货 数量
1 mg ¥819
In-stock
5 mg   询价  
10 mg   询价  

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Other Forms of 1-Palmitoyl-sn-glycerol 3-phosphate:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is an endogenous metabolite. 1-Palmitoyl-sn-glycerol 3-phosphate can be used for the research of non‐alcoholic fatty liver disease[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 EC50
290 nM
Compound: LPA (16:0)
Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay
Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay
[PMID: 23395664]
HEK293 EC50
580 nM
Compound: LPA (16:0)
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay
[PMID: 23395664]
HEK293 EC50
68 nM
Compound: LPA (16:0)
Agonist activity at human LPA5 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425
Agonist activity at human LPA5 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425
[PMID: 23395664]
HEK293 EC50
71 nM
Compound: LPA (16:0)
Agonist activity at human LPA1 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay
Agonist activity at human LPA1 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay
[PMID: 23395664]
HEK293 EC50
84 nM
Compound: LPA (16:0)
Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425
Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425
[PMID: 23395664]
HEK293 EC50
930 nM
Compound: LPA (16:0)
Agonist activity at human LPA6 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425
Agonist activity at human LPA6 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425
[PMID: 23395664]
分子量

410.48

Formula

C19H39O7P

CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验: 

DMSO 中的溶解度 : 2.5 mg/mL (6.09 mM; 超声加热助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.4362 mL 12.1809 mL 24.3617 mL
5 mM 0.4872 mL 2.4362 mL 4.8723 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥99.0%

参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4362 mL 12.1809 mL 24.3617 mL 60.9043 mL
5 mM 0.4872 mL 2.4362 mL 4.8723 mL 12.1809 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
1-Palmitoyl-sn-glycerol 3-phosphate
目录号:
HY-126967A
需求量: