1. Anti-infection Metabolic Enzyme/Protease
  2. Antibiotic Bacterial Farnesyl Transferase
  3. 10'-Desmethoxystreptonigrin

10'-Desmethoxystreptonigrin 是 Ras 法呢基转移酶 (Ras Farnesyltransferase) 的抑制剂,IC50 为 21 μM。10'-Desmethoxystreptonigrin 是一种具有抗菌活性的广谱抗生素。10'-Desmethoxystreptonigrin 对 P388 白血病具有抗肿瘤活性,且无显著的细胞毒性 (LD50 为 8.8 mg/kg)。

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10'-Desmethoxystreptonigrin Chemical Structure

10'-Desmethoxystreptonigrin Chemical Structure

CAS No. : 136803-89-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD50 is 8.8 mg/kg)[1].

IC50 & Target

IC50: 21 μM (Ras Farnesyltransferase)

分子量

476.44

Formula

C24H20N4O7

CAS 号
结构分类
初始来源

Streptomyces albus

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
10'-Desmethoxystreptonigrin
目录号:
HY-137139
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