2. Anti-infection Metabolic Enzyme/Protease
  3. Antibiotic Bacterial Farnesyl Transferase
  4. 10'-Desmethoxystreptonigrin

10'-Desmethoxystreptonigrin 是 Ras 法呢基转移酶 (Ras Farnesyltransferase) 的抑制剂，IC50 为 21 μM。10'-Desmethoxystreptonigrin 是一种具有抗菌活性的广谱抗生素。10'-Desmethoxystreptonigrin 对 P388 白血病具有抗肿瘤活性，且无显著的细胞毒性 (LD50 为 8.8 mg/kg)。

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10'-Desmethoxystreptonigrin Chemical Structure

10'-Desmethoxystreptonigrin Chemical Structure

CAS No. : 136803-89-9

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10'-Desmethoxystreptonigrin 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD50 is 8.8 mg/kg)[1].

IC50 & Target

IC50: 21 μM (Ras Farnesyltransferase)
分子量

476.44

Formula

C24H20N4O7
CAS 号
结构分类
初始来源

Streptomyces albus
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

10'-Desmethoxystreptonigrin 相关分类

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Keywords:

10'-Desmethoxystreptonigrin136803-89-9AntibioticBacterialFarnesyl TransferaseFtaseantibacterialleukemiaStreptonigrinEtoposideTeniposideInhibitorinhibitorinhibit

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