2. Metabolic Enzyme/Protease
  3. 11β-HSD
  4. 11β-HSD1-IN-14

11β-HSD1-IN-14 (Compound 17) 是 11β-羟基类固醇脱氢酶 1 型 (11β-HSD1) 的选择性抑制剂，IC50 为 74 nM (h 11β-HSD1) 和 603 nM (表达 HSD1 的 HEK293 细胞)。

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11β-HSD1-IN-14 Chemical Structure

11β-HSD1-IN-14 Chemical Structure

CAS No. : 946394-50-9

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11β-HSD1-IN-14 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

11β-HSD1-IN-14 (Compound 17) is a selective inhibitor for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1), with IC50 of 74 nM for human HSD1, and 603 nM for HSD1 expressed HEK293 cell[1].

IC50 & Target

IC50: 74 nM (h 11β-HSD1)
分子量

447.47

Formula

C22H20F3N3O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

11β-HSD1-IN-14 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11β-HSD1-IN-14946394-50-911β-HSD11beta-HSD11β-hydroxysteroid dehydrogenases11 beta-hydroxysteroid dehydrogenaseinsulin resistancedyslipidemiatype II diabetesInhibitorinhibitorinhibit

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