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  4. 15(R)-15-Methyl Prostaglandin F2α

15(R)-15-Methyl Prostaglandin F2α  (Synonyms: 15(R)-Carboprost; 15(R)-15-methyl PGF2α)

目录号: HY-139124
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15(R)-15-Methyl Prostaglandin F2α (15(R)-Carboprost; 15(R)-15-methyl PGF2α) 是一种代谢稳定的 PGF2α 类似物。15(R)-15-Methyl Prostaglandin F2α 是一种无活性的前体药物 PGF 激动剂，口服后可由胃酸激活。15(R)-15-Methyl Prostaglandin F2α 的酸催化差向异构化可将其转化为活性 15(S)-异构体。15(S)-异构体在恒河猴体内注射剂量约为 12 mg/只时可诱发黄体溶解，而 15(R)-异构体则不会。

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15(R)-15-Methyl Prostaglandin F2α Chemical Structure

15(R)-15-Methyl Prostaglandin F2α Chemical Structure

CAS No. : 35864-81-4

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15(R)-15-Methyl Prostaglandin F2α 相关抗体

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生物活性

15(R)-15-Methyl Prostaglandin F2α (15(R)-Carboprost; 15(R)-15-methyl PGF2α) is a metabolically stable analog of PGF2α. 15(R)-15-Methyl Prostaglandin F2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-Methyl Prostaglandin F2α converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.

分子量

368.51

Formula

C21H36O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

15(R)-15-Methyl Prostaglandin F2α 相关分类

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Keywords:

15(R)-15-Methyl Prostaglandin F2α35864-81-415(R)-Carboprost 15(R)-15-methyl PGF2αOthersInhibitorinhibitorinhibit

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