2. 天然产物
  3. 海洋天然产物 其他类
  4. 其他海洋生物
  5. 18-O-Demethylpederin

18-O-Demethylpederin 是一种 pederin 类似物。Pederin 是首次从隐翅虫属昆虫中提取的天然聚酮化合物，是一种非蛋白质昆虫毒素，具有广谱的生物活性，包括抗菌、抗病毒、抗肿瘤等。

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18-O-Demethylpederin Chemical Structure

18-O-Demethylpederin Chemical Structure

CAS No. : 2120362-33-4

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18-O-Demethylpederin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

18-O-Demethylpederin is a pederin analogue. Pederin is a natural polyketide compound extracted from Paederus for the first time. It is a non-protein insect toxin with a broad spectrum of biological activities, including antibacterial, antiviral, and antitumor[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 GI50
2 nM
Compound: 1
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by SRB assay
[PMID: 28696720]
HT-29 GI50
2 nM
Compound: 1
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB assay
[PMID: 28696720]
MDA-MB-231 GI50
2 nM
Compound: 1
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by SRB assay
[PMID: 28696720]
PSN1 GI50
2 nM
Compound: 1
Antiproliferative activity against human PSN1 cells assessed as growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human PSN1 cells assessed as growth inhibition after 72 hrs by SRB assay
[PMID: 28696720]
分子量

489.60

Formula

C24H43NO9
CAS 号
结构分类
初始来源

insects, lichen, and marine sponges
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

18-O-Demethylpederin 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

18-O-Demethylpederin2120362-33-4OthersInhibitorinhibitorinhibit

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