1. 天然产物
  2. 植物 萜类
  3. 菊科 唇形科 二萜
  4. Ambrosia camphorata (Greene) W.W.Payne
  5. (19R)-13-Deoxy-19-hydroxyenmein

(19R)-13-Deoxy-19-hydroxyenmein 

目录号: HY-N12253
产品使用指南

(19R)-13-Deoxy-19-hydroxyenmein 是enmein型二萜类似物的母体化合物。(19R)-13-Deoxy-19-Hydroxyenmein 具有抗增殖活性,对人癌细胞系 K562、MGC-803、CaEs-17 和 Bel-7402 的 IC50 值分别为 0.41、0.85、0.43、1.89 μM

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(19R)-13-Deoxy-19-hydroxyenmein Chemical Structure

(19R)-13-Deoxy-19-hydroxyenmein Chemical Structure

CAS No. : 16763-48-7

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规格 价格 是否有货 数量
1 mg ¥2208
1 - 2 周
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(19R)-13-Deoxy-19-hydroxyenmein is the parent compound of enmein-type diterpenoid analogs. (19R)-13-Deoxy-19-hydroxyenmein has anti-proliferative activities with IC50 values of 0.41, 0.85, 0.43, 1.89 μM against human cancer cell lines K562, MGC-803, CaEs-17, and Bel-7402, respectively[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
50.86 μM
Compound: 2
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
[PMID: 22483090]
Bel-7402 IC50
32.09 μM
Compound: 2
Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
[PMID: 29407983]
Bel-7402 IC50
32.96 μM
Compound: 10
Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay
Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay
[PMID: 23644204]
Bel-7402 IC50
32.96 μM
Compound: 2
Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay
Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay
[PMID: 22483090]
Bel7402/5-FU IC50
44.27 μM
Compound: 2
Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay
Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay
[PMID: 29407983]
HeLa IC50
60.7 μM
Compound: 2
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
[PMID: 22483090]
HL-60 IC50
28.07 μM
Compound: 2
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
[PMID: 29407983]
K562 IC50
8.11 μM
Compound: 10
Cytotoxicity against human K562 cells after 72 hrs by MTT assay
Cytotoxicity against human K562 cells after 72 hrs by MTT assay
[PMID: 23644204]
K562 IC50
8.11 μM
Compound: 2
Cytotoxicity against human K562 cells after 72 hrs by MTT assay
Cytotoxicity against human K562 cells after 72 hrs by MTT assay
[PMID: 22483090]
L02 IC50
27.06 μM
Compound: 2
Antiproliferative activity against human LO2 cells after 72 hrs by MTT assay
Antiproliferative activity against human LO2 cells after 72 hrs by MTT assay
[PMID: 29407983]
MCF7 IC50
68.2 μM
Compound: 2
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
[PMID: 22483090]
MGC-803 IC50
14.21 μM
Compound: 10
Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
[PMID: 23644204]
PC-3 IC50
30.55 μM
Compound: 2
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
[PMID: 29407983]
分子量

362.42

Formula

C20H26O6

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(19R)-13-Deoxy-19-hydroxyenmein
目录号:
HY-N12253
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