1. GPCR/G Protein Neuronal Signaling
  2. Adenosine Receptor Amyloid-β
  3. 2-Hexynyl-5′-N-ethylcarboxamidoadenosine

2-Hexynyl-5′-N-ethylcarboxamidoadenosine  (Synonyms: HENECA; 2-Hexynyl-NECA)

目录号: HY-137370
产品使用指南

2-Hexynyl-5′-N-ethylcarboxamidoadenosine (HENECA) 是一种选择性 A2A 腺苷受体 激动剂。2-Hexynyl-5′-N-ethylcarboxamidoadenosine 可增加细胞内 cAMP 水平,并抑制 TNFα 诱发的 MMP-3 释放。2-Hexynyl-5′-N-ethylcarboxamidoadenosine 可诱导 SH-SY5Y 细胞中 Aβ42 的产生。

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2-Hexynyl-5′-N-ethylcarboxamidoadenosine Chemical Structure

2-Hexynyl-5′-N-ethylcarboxamidoadenosine Chemical Structure

CAS No. : 141018-30-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2-Hexynyl-5′-N-ethylcarboxamidoadenosine (HENECA) is a selective A2A adenosine receptor agonist. 2-Hexynyl-5′-N-ethylcarboxamidoadenosine increases intracellular cAMP level, and inhibits TNFα-evoked MMP-3 release. 2-Hexynyl-5′-N-ethylcarboxamidoadenosine induces Aβ42 production in SH-SY5Y cells[1][2][3].

IC50 & Target[1]

A2AR

 

分子量

388.42

Formula

C18H24N6O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

2-Hexynyl-5′-N-ethylcarboxamidoadenosine 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
2-Hexynyl-5′-N-ethylcarboxamidoadenosine
目录号:
HY-137370
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