1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Tyrosinase Endogenous Metabolite
  3. 2-Ketoglutaric acid-13C2

2-Ketoglutaric acid-13C2  (Synonyms: α-酮戊二酸-13C2; Alpha-Ketoglutaric acid-13C2)

目录号: HY-W013636S4
产品使用指南

2-Ketoglutaric acid-13C2是氘代标记的2-Ketoglutaric acid。2-Ketoglutaric acid (Alpha-Ketoglutaric acid) 是 Krebs 循环中 ATP 或 GTP 产生的中间体。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶 (tyrosinase) 的可逆抑制剂 (IC50=15 mM)。

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2-Ketoglutaric acid-<sup>13</sup>C<sub>2</sub> Chemical Structure

2-Ketoglutaric acid-13C2 Chemical Structure

CAS No. : 123953-28-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2-Ketoglutaric acid-13C2 is a deuterated labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

148.08

Formula

C313C2H6O5

CAS 号
中文名称

α-酮戊二酸-13C2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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