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  3. Isotope-Labeled Compounds
  4. 2-Ketoglutaric acid-13C

2-Ketoglutaric acid-13C  (Synonyms: α-酮戊二酸-13C; Alpha-Ketoglutaric acid-13C)

目录号: HY-W013636S3
COA 产品使用指南

摩尔计算器

2-Ketoglutaric acid-13C (Alpha-Ketoglutaric acid-13C) 是一种 13C 标记的 2-Ketoglutaric acid (HY-W013636)。2-Ketoglutaric acid (Alpha-Ketoglutaric acid) 是 Krebs 循环中 ATP 或 GTP 产生的中间体。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶 (tyrosinase) 的可逆抑制剂 (IC50=15 mM)。

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2-Ketoglutaric acid-<sup>13</sup>C Chemical Structure

2-Ketoglutaric acid-13C Chemical Structure

CAS No. : 108395-15-9

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规格 价格 是否有货
500 μg ￥9350
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Other Forms of 2-Ketoglutaric acid-13C:

2-Ketoglutaric acid-13C 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2-Ketoglutaric acid-13C (Alpha-Ketoglutaric acid-13C) is a 13C labeled 2-Ketoglutaric acid (HY-W013636)[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2][3].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

2-Ketoglutaric acid-13C 相关抗体:
分子量

147.09

Formula

C413CH6O5
CAS 号
非标记 CAS

328-50-7
性状

固体

颜色

White to light yellow

中文名称

α-酮戊二酸-13C
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥97.0%

COA (190 KB)

产品使用指南 (1538 KB)
参考文献

2-Ketoglutaric acid-13C 相关分类

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Keywords:

2-Ketoglutaric acid-13C108395-15-9Alpha-Ketoglutaric acid-13Cα-酮戊二酸-13CIsotope-Labeled CompoundsintermediateprecursorTCAcarbonskeletonInhibitorinhibitorinhibit

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