2. Cell Cycle/DNA Damage Cytoskeleton Apoptosis
  3. Microtubule/Tubulin Apoptosis
  4. 3-(3-Phenoxybenzyl)amino-β-carboline

3-(3-Phenoxybenzyl)amino-β-carboline 

目录号: HY-150511
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摩尔计算器

3-(3-Phenoxybenzyl)amino-β-carboline 是一种有效的微管蛋白 (tubulin) 抑制剂。3-(3-Phenoxybenzyl)amino-β-carboline 促进 αβ- 微管蛋白异二聚体的选择性降解。3-(3-Phenoxybenzyl)amino-β-carboline 诱导 G2/M 期细胞周期阻滞和凋亡 (apoptosis)。3-(3-Phenoxybenzyl)amino-β-carboline 具有抗癌活性。

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3-(3-Phenoxybenzyl)amino-β-carboline Chemical Structure

3-(3-Phenoxybenzyl)amino-β-carboline Chemical Structure

CAS No. : 1327080-54-5

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3-(3-Phenoxybenzyl)amino-β-carboline 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3-(3-Phenoxybenzyl)amino-β-carboline is a potent tubulin inhibitor. 3-(3-Phenoxybenzyl)amino-β-carboline promotes selective degradation of αβ-tubulin heterodimers. 3-(3-Phenoxybenzyl)amino-β-carboline induces G2/M phase cell cycle arrest and apoptosis. 3-(3-Phenoxybenzyl)amino-β-carboline exhibits anticancer activity[1].

体外研究
(In Vitro)

3-(3-Phenoxybenzyl)amino-β-carboline specifically denatures tubulin, making it prone to aggregation that predisposes it to ubiquitinylation and then degradation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

3-(3-Phenoxybenzyl)amino-β-carboline 相关抗体:
分子量

365.43

Formula

C24H19N3O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3-(3-Phenoxybenzyl)amino-β-carboline 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-(3-Phenoxybenzyl)amino-β-carboline1327080-54-5Microtubule/TubulinApoptosisHeLa cellsHct116H460SU-DHL-6 cellsanticancerInhibitorinhibitorinhibit

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