2. Metabolic Enzyme/Protease
  3. 17β-HSD
  4. 3-Acetyl-7-Hydroxycoumarin

3-Acetyl-7-Hydroxycoumarin  (Synonyms: 3-乙酰基-7-羟基-苯并吡喃-2-酮)

目录号: HY-W267205
产品使用指南 技术支持

3-Acetyl-7-Hydroxycoumarin (Compound 2) 是一种高选择性 17- β-羟基类固醇脱氢酶 1 型 (17β-HSD1) 抑制剂。3-Acetyl-7-Hydroxycoumarin 对 17β-HSD1 的抑制作用在 6 μM 下达到 57%。3-Acetyl-7-Hydroxycoumarin 有望用于乳腺癌、子宫内膜异位症等激素依赖性疾病的研究。

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3-Acetyl-7-Hydroxycoumarin Chemical Structure

3-Acetyl-7-Hydroxycoumarin Chemical Structure

CAS No. : 10441-27-7

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3-Acetyl-7-Hydroxycoumarin 相关抗体

Top Publications Citing Use of Products

查看 17β-HSD 亚型特异性产品:

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17β-HSD2 17β-HSD5/AKR1C3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17β-HSD1 at 6 μM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis[1].

分子量

204.18

Formula

C11H8O4
CAS 号
中文名称

3-乙酰基-7-羟基-苯并吡喃-2-酮
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3-Acetyl-7-Hydroxycoumarin 相关分类

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Keywords:

3-Acetyl-7-Hydroxycoumarin10441-27-73-乙酰基-7-羟基-苯并吡喃-2-酮17β-HSD17beta-HSD17β-hydroxysteroid dehydrogenases17 beta-hydroxysteroid dehydrogenase17-beta-hydroxysteroid dehydrogenase type 1breast cancer and endometriosisInhibitorinhibitorinhibit

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