2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 3’-Azido-3’-deoxyinosine

3’-Azido-3’-deoxyinosine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。3’-Azido-3’-deoxyinosine 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。

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3’-Azido-3’-deoxyinosine Chemical Structure

3’-Azido-3’-deoxyinosine Chemical Structure

CAS No. : 946497-27-4

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3’-Azido-3’-deoxyinosine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3’-Azido-3’-deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3’-Azido-3’-deoxyinosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

分子量

291.27

Formula

C11H13N7O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3’-Azido-3’-deoxyinosine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

3’-Azido-3’-deoxyinosine946497-27-4Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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