2. Others Protein Tyrosine Kinase/RTK
  3. Isotope-Labeled Compounds FLT3
  4. 3-Hydroxy Midostaurin-d5

3-Hydroxy Midostaurin-d5  (Synonyms: CGP52421-d5)

目录号: HY-108263S
产品使用指南

摩尔计算器

3-Hydroxy Midostaurin-d5 是 3-Hydroxy Midostaurin 的氘代化合物标准品。3-Hydroxy Midostaurin 是 PKC412 的代谢产物，可有效抑制 FMS 样酪氨酸激酶 3 (FLT3) 自磷酸化，在培养基和血浆中的 IC50 值分别约为 132 nM 和 9.8 μM。

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3-Hydroxy Midostaurin-d<sub>5</sub> Chemical Structure

3-Hydroxy Midostaurin-d5 Chemical Structure

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Other Forms of 3-Hydroxy Midostaurin-d5:

3-Hydroxy Midostaurin-d5 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3-Hydroxy Midostaurin-d5 is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

分子量

591.67

Formula

C35H25D5N4O5
非标记 CAS

179237-49-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3-Hydroxy Midostaurin-d5 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Hydroxy Midostaurin-d5CGP52421-d5Isotope-Labeled CompoundsFLT3Cluster of differentiation antigen 135CD135Fms like tyrosine kinase 3Inhibitorinhibitorinhibit

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