2. Epigenetics TGF-beta/Smad Others
  3. PKC Drug Derivative
  4. 3-Methyl-L-tyrosine

3-Methyl-L-tyrosine 是一种 L-Tyrosine (HY-N0473) 衍生物。结构上，3-Methyl-L-tyrosine 在 L-Tyrosine 的芳香环上第三位置有一个甲基修饰。作为蛋白酪氨酸激酶 Csk 的底物，3-Methyl-L-tyrosine 的相对催化效率 (kcat/Km) 为 L-Tyrosine 的 38 %，表明甲基修饰对 Gsk 的处理效率有一定影响。3-Methyl-L-tyrosine 有助于深入理解 Gsk 对其底物的分子识别机制，对开发针对特定 Gsk 抑制剂有重要应用价值。

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3-Methyl-L-tyrosine Chemical Structure

3-Methyl-L-tyrosine Chemical Structure

CAS No. : 17028-03-4

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3-Methyl-L-tyrosine 相关抗体

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生物活性

3-Methyl-L-tyrosine is a derivative of L-Tyrosine (HY-N0473). Structurally, 3-Methyl-L-tyrosine features a methyl modification at the third position of the aromatic ring of L-Tyrosine. As a substrate for the protein tyrosine kinase Csk, 3-Methyl-L-tyrosine's relative catalytic efficiency (kcat/Km) is 38% of L-Tyrosine, indicating that the methyl modification impacts the processing efficiency of Gsk significantly. 3-Methyl-L-tyrosine helps to deepen the understanding of Gsk's molecular recognition mechanisms of its substrates, which is crucial for developing specific inhibitors targeting Gsk[1].

分子量

195.22

Formula

C10H13NO3
CAS 号
运输条件

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储存方式

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3-Methyl-L-tyrosine 相关分类

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Keywords:

3-Methyl-L-tyrosine17028-03-4PKCDrug DerivativeProtein kinase CDrug derivativeInhibitorinhibitorinhibit

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