1. 天然产物
  2. 植物 黄酮类
  3. 天门冬科
  4. 绵枣儿
  5. 4'-Demethyleucomin

4'-Demethyleucomin  (Synonyms: O-Demethyleucomin)

目录号: HY-N1892
产品使用指南 技术支持

4'-Demethyleucomin (O-Demethyleucomin) 是一种黄酮类化合物,可以从绵枣儿属植物中分离得到。

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4'-Demethyleucomin Chemical Structure

4'-Demethyleucomin Chemical Structure

CAS No. : 34818-83-2

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  • 生物活性

  • 纯度 & 产品资料

生物活性

4'-Demethyleucomin (O-Demethyleucomin) is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum hydropiper[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
3T3-L1 IC50
> 100 μM
Compound: 9
Antiadipogenic activity against mouse 3T3L1 cells assessed as inhibition of differentiation after 7 days by oil-red O staining
Antiadipogenic activity against mouse 3T3L1 cells assessed as inhibition of differentiation after 7 days by oil-red O staining
[PMID: 19757853]
ARPE-19 GI50
> 100 μM
Compound: 34
Antiproliferative activity against human ARPE19 assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
Antiproliferative activity against human ARPE19 assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
[PMID: 30951308]
BTI-TN-5B1-4 IC50
11.46 μM
Compound: 1h
Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorimetric method
Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorimetric method
[PMID: 21405131]
BTI-TN-5B1-4 IC50
8.61 nM
Compound: 1h
Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorimetric method
Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorimetric method
[PMID: 21405131]
HT-29 IC50
> 20 μM
Compound: 11
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth incubated for 72 hrs
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth incubated for 72 hrs
[PMID: 26147490]
MDA-MB-435 IC50
> 20 μM
Compound: 11
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell growth incubated for 72 hrs
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell growth incubated for 72 hrs
[PMID: 26147490]
Y79 GI50
> 100 μM
Compound: 34
Cytotoxicity against human Y79 cells assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
Cytotoxicity against human Y79 cells assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
[PMID: 30951308]
分子量

284.26

Formula

C16H12O5

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
4'-Demethyleucomin
目录号:
HY-N1892
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