2. 天然产物
  3. 植物 生物碱
  4. 苦木科 喹啉类生物碱
  5. 臭椿
  6. 4-Hydroxycanthin-6-one

4-Hydroxycanthin-6-one 是从树木Ailanthus altissima的茎皮中分离出的一种新型类喹啉生物碱。研究还发现了其他五种已知化合物。通过物理和光谱数据的解释，确定了新化合物的结构，并通过电子圆二色谱和量子化学计算确定了其绝对构型。这些化合物在RAW 264.7细胞中对脂多糖 (LPS) 诱导的一氧化氮 (NO) 生成具有显著的抑制活性，显示出潜在的抗炎特性。

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4-Hydroxycanthin-6-one Chemical Structure

4-Hydroxycanthin-6-one Chemical Structure

CAS No. : 106941-27-9

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4-Hydroxycanthin-6-one 相关抗体

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  • 生物活性

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生物活性

4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of the tree Ailanthus altissima. Five other known compounds were also found in the study. The structures of the new compounds were determined by interpretation of physical and spectroscopic data, and their absolute configurations were determined by electronic circular dichroism spectroscopy and quantum chemical calculations. These compounds showed significant inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, showing potential anti-inflammatory properties[1].

分子量

236.23

Formula

C14H8N2O2
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

4-Hydroxycanthin-6-one 相关分类

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Keywords:

4-Hydroxycanthin-6-one106941-27-9OthersInhibitorinhibitorinhibit

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