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  3. 5-Acetamide-Butenolide

5-Acetamide-Butenolide  (Synonyms: Butenolide)

目录号: HY-W402074
产品使用指南

5-Acetamide-Butenolide (butenolide) 是一种具有促氧化活性的真菌毒素,在 Fusarium 中发现。5-Acetamide-Butenolide 破坏新生大鼠心肌细胞线粒体膜电位。5-Acetamide-Butenolide 还能诱导离体大鼠心肌线粒体产生硫代巴比妥酸反应物质 (TBARS)。5-Acetamide-Butenolide 增加活性氧 (ROS) 的产生,降低 GSH 水平,降低 HepG2 细胞的活力。

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5-Acetamide-Butenolide Chemical Structure

5-Acetamide-Butenolide Chemical Structure

CAS No. : 16275-44-8

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生物活性

5-Acetamide-Butenolide (butenolide) is a mycotoxin with pro-oxidant activity, which is found in Fusarium. 5-Acetamide-Butenolide disrupts the mitochondrial membrane potential in primary neonatal rat cardiomyocytes. 5-Acetamide-Butenolide also induces the production of thiobarbituric acid reactive substances (TBARS) in isolated rat myocardial mitochondria. 5-Acetamide-Butenolide increases the production of reactive oxygen species (ROS), decreases the levels of GSH and reduces the viability of HepG2 cells[1][2][3].

分子量

141.12

Formula

C6H7NO3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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5-Acetamide-Butenolide
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HY-W402074
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