2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. 5-HT6/5-HT2A receptor ligand-2

5-HT6/5-HT2A receptor ligand-2 

目录号: HY-146077
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摩尔计算器

5-HT6/5-HT2A receptor ligand-2 (化合物 42) 是一种可透过血脑屏障的 5-HT6/5-HT2A 的双拮抗剂 , Ki 值分别为 25 nM 和 32 nM。5-HT6/5-HT2A receptor ligand-2 具有促认知特性。

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5-HT6/5-HT2A receptor ligand-2 Chemical Structure

5-HT6/5-HT2A receptor ligand-2 Chemical Structure

CAS No. : 2411088-16-7

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5-HT6/5-HT2A receptor ligand-2 相关抗体

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查看 5-HT Receptor 亚型特异性产品:

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5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

5-HT6/5-HT2A receptor ligand-2 (compound 42) is a brain-penetrant dual 5-HT6/5-HT2A receptor antagonist, with a Ki of 25 nM and 32 nM, respectively. 5-HT6/5-HT2A receptor ligand-2 shows pro-cognitive properties[1].

IC50 & Target[1]

5-HT6 Receptor

25 nM (Ki)

5-HT2A Receptor

32 nM (Ki)

分子量

351.37

Formula

C20H18FN3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5-HT6/5-HT2A receptor ligand-2 相关分类

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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-HT6/5-HT2A receptor ligand-22411088-16-75-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorcognitive dysfunctionInhibitorinhibitorinhibit

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5-HT6/5-HT2A receptor ligand-2
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