2. Immunology/Inflammation
  3. NO Synthase
  4. (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one 

目录号: HY-N0997
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(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one (compound7) 是一种由 Curcuma kwangsiensis 植物中分离的天然产物。(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one 在巨噬细胞中能抑制 LPS 诱导产生的 NO，IC50 为 8.93 μM。

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(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one Chemical Structure

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one Chemical Structure

CAS No. : 1251830-57-5

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(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one (compound7) is a nature product isolated from rhizomes of Curcuma kwangsiensis. (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one has inhibitory effect on NO production induced by LPS in macrophages with an IC50 value of 8.93 μM[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
B16-4A5 IC50
1.24 μM
Compound: 5
Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
[PMID: 23910596]
RAW264.7 IC50
8.93 μM
Compound: 7
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production by MTT assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production by MTT assay
[PMID: 20879743]
分子量

296.36

Formula

C19H20O3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one 相关分类

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Keywords:

(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one1251830-57-5NO SynthaseNitric oxide synthasesNOSCurcuma kwangsiensisAnticancerAnti-inflammatoryLPSMacrophagesInhibitorinhibitorinhibit

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