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  4. 7α,27-Dihydroxycholesterol

7α,27-Dihydroxycholesterol  (Synonyms: 7α,27-二羟基胆固醇)

目录号: HY-W414548
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7α,27-Dihydroxycholesterol 是一种以氧化侧链为特征的氧固醇，由 27-羟基胆固醇 (27-OHC) 羟基化产生；它是各种病理状况的脂质组学分析中感兴趣的代谢物，包括神经系统疾病、史密斯-莱姆利-奥皮茨综合征、肥胖代谢综合征和糖尿病。值得注意的是，7α,27-二羟基胆固醇的水平在脂多糖活化后会降低，它还可以作为 Epstein-Barr 病毒诱导基因 2 (EBI2) 的配体。此外，7α,27-二羟基胆固醇 (7α25-OHC) 的结构异构体存在。

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7α,27-Dihydroxycholesterol Chemical Structure

7α,27-Dihydroxycholesterol Chemical Structure

CAS No. : 4725-24-0

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7α,27-Dihydroxycholesterol 相关抗体

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生物活性

7α,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC); it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7α,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2). Additionally, 7α,27-di-OHC exists as a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC).

分子量

418.65

Formula

C27H46O3
CAS 号
中文名称

7α,27-二羟基胆固醇
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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7α,27-Dihydroxycholesterol 相关分类

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Keywords:

7α,27-Dihydroxycholesterol4725-24-07α,27-二羟基胆固醇OthersInhibitorinhibitorinhibit

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