2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 7α-Hydroxy-4-cholesten-3-one-d7

7α-Hydroxy-4-cholesten-3-one-d7 

目录号: HY-113259S 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

7α-Hydroxy-4-cholesten-3-one-d7 是 7α-Hydroxy-4-cholesten-3-one 的氘代物。7α-Hydroxy-4-cholesten-3-one 是一种由胆固醇合成胆汁酸的中间体。7α-Hydroxy-4-cholesten-3-one 是一种孕烷 X 受体 (PXR) 激动剂。7α-Hydroxy-4-cholesten-3-one 是胆汁酸流失，肠易激综合征和其他与胆汁酸生物合成缺陷有关的疾病的生物标志物。7α-Hydroxy-choles

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7α-Hydroxy-4-cholesten-3-one-d<sub>7</sub> Chemical Structure

7α-Hydroxy-4-cholesten-3-one-d7 Chemical Structure

CAS No. : 2260669-17-6

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规格 价格 是否有货 数量
500 μg 现货 询价
5 mg 询价

* Please select Quantity before adding items.

Customer Review

Other Forms of 7α-Hydroxy-4-cholesten-3-one-d7:

7α-Hydroxy-4-cholesten-3-one-d7 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

7α-Hydroxy-4-cholesten-3-one-d7 is the deuterium labeled 7α-Hydroxy-4-cholesten-3-one. 7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

7α-Hydroxy-4-cholesten-3-one-d7 相关抗体:
分子量

407.68

Formula

C27H37D7O2
CAS 号
非标记 CAS
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 100 mg/mL (245.29 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.4529 mL 12.2645 mL 24.5290 mL
5 mM 0.4906 mL 2.4529 mL 4.9058 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥98.0%

COA (176 KB)

产品使用指南 (1538 KB)
参考文献

7α-Hydroxy-4-cholesten-3-one-d7 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4529 mL 12.2645 mL 24.5290 mL 61.3226 mL
5 mM 0.4906 mL 2.4529 mL 4.9058 mL 12.2645 mL
10 mM 0.2453 mL 1.2265 mL 2.4529 mL 6.1323 mL
15 mM 0.1635 mL 0.8176 mL 1.6353 mL 4.0882 mL
20 mM 0.1226 mL 0.6132 mL 1.2265 mL 3.0661 mL
25 mM 0.0981 mL 0.4906 mL 0.9812 mL 2.4529 mL
30 mM 0.0818 mL 0.4088 mL 0.8176 mL 2.0441 mL
40 mM 0.0613 mL 0.3066 mL 0.6132 mL 1.5331 mL
50 mM 0.0491 mL 0.2453 mL 0.4906 mL 1.2265 mL
60 mM 0.0409 mL 0.2044 mL 0.4088 mL 1.0220 mL
80 mM 0.0307 mL 0.1533 mL 0.3066 mL 0.7665 mL
100 mM 0.0245 mL 0.1226 mL 0.2453 mL 0.6132 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7α-Hydroxy-4-cholesten-3-one-d72260669-17-6Endogenous MetaboliteInhibitorinhibitorinhibit

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