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  3. 7-Methoxy-β-carboline-1-propionic acid

7-Methoxy-β-carboline-1-propionic acid 

目录号: HY-N7173
产品使用指南

7-Methoxy-β-carboline-1-propionic acid (compound 46) 是一种具有细胞毒性和抗疟疾的化合物。7-Methoxy-β-carboline-1-propionic acid 可以从东革阿里的根中提取。

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7-Methoxy-β-carboline-1-propionic acid Chemical Structure

7-Methoxy-β-carboline-1-propionic acid Chemical Structure

CAS No. : 137756-13-9

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

7-Methoxy-β-carboline-1-propionic acid (compound 46) is a cytotoxic and antimalarial compound. 7-Methoxy-β-carboline-1-propionic acid can be extracted from the roots of Eurycoma longifolia[1].

IC50 & Target

Plasmodium

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 ED50
> 20 μg/mL
Compound: 7-methoxy-beta-carboline-1-propionicacid
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
[PMID: 14575431]
Calu-3 CC50
> 100 μM
Compound: Table 1, R8C2
Cytotoxicity against human Calu-3 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
Cytotoxicity against human Calu-3 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
HCT-8 CC50
79 μM
Compound: Table 1, R8C2
Cytotoxicity against human HCT-8 cells assessed as redcution in cell viability incubated for 96 hrs by PrestoBlue reagent based assay
Cytotoxicity against human HCT-8 cells assessed as redcution in cell viability incubated for 96 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
HepG2 CC50
> 100 μM
Compound: Table 1, R8C2
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
MCF7 ED50
> 20 μg/mL
Compound: 7-methoxy-beta-carboline-1-propionicacid
Cytotoxicity against human MCF7 cells by SRB assay
Cytotoxicity against human MCF7 cells by SRB assay
[PMID: 14575431]
MRC5 CC50
> 100 μM
Compound: Table 1, R8C2
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
Vero CC50
> 100 μM
Compound: Table 1, R8C2
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
分子量

270.28

Formula

C15H14N2O3

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

7-Methoxy-β-carboline-1-propionic acid 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
7-Methoxy-β-carboline-1-propionic acid
目录号:
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