2. Membrane Transporter/Ion Channel
  3. P-glycoprotein
  4. 9,10-trans-Dehydroepothilone D

9,10-trans-Dehydroepothilone D 

目录号: HY-106265
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摩尔计算器

9,10-trans-Dehydroepothilone D 对过表达 P-glycoprotein 的紫杉醇耐药细胞系显示出抗增殖活性。9,10-trans-Dehydroepothilone D 还具有微管聚合活性。9,10-trans-Dehydroepothilone D 是 Seco acid 通过内酯化反应获得的，有望用于癌症的研究。

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9,10-trans-Dehydroepothilone D Chemical Structure

9,10-trans-Dehydroepothilone D Chemical Structure

CAS No. : 350493-61-7

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9,10-trans-Dehydroepothilone D 相关抗体

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  • 生物活性

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生物活性

9,10-trans-Dehydroepothilone D shows an antiproliferative activity against a paclitaxel-resistant cell lines overexpressing P-glycoprotein. 9,10-trans-Dehydroepothilone D also shows tubulin polymerization activity. 9,10-trans-Dehydroepothilone D is given by lactonization of Seco acid, which is promising for research of cancers[1].

分子量

489.67

Formula

C27H39NO5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

9,10-trans-Dehydroepothilone D 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

9,10-trans-Dehydroepothilone D350493-61-7P-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243antiproliferativepaclitaxel-resistant cell linetubulin polymerization activitycancersInhibitorinhibitorinhibit

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