1. Anti-infection
  2. Bacterial
  3. 9-Methylstreptimidone

9-Methylstreptimidone  (Synonyms: Antibiotic TS 885; NSC 248958)

目录号: HY-134090
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9-Methylstreptimidone (Antibiotic TS 885; NSC 248958)是一种微生物代谢物,最初从链霉菌 S-885 中分离出来,具有抗真菌和抗病毒活性。它对多种真菌有活性,包括 S. sake、S. fragilis、R. rubra、T. rubra 和 C. albidus(MIC=4-20 μg/mL),并且在体外对脊髓灰质炎病毒、水泡性口炎病毒 (VSV) 和新城疫病毒 (NDV) 具有抗病毒活性(MIC=0.02 μg/mL)。在感染前使用 9-Methylstreptimidone (Antibiotic TS 885; NSC 248958)可提高感染流感 A2 (H2N2) 或白色念珠菌的小鼠模型的存活率。

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9-Methylstreptimidone Chemical Structure

9-Methylstreptimidone Chemical Structure

CAS No. : 51867-94-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.

分子量

307.38

Formula

C17H25NO4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

9-Methylstreptimidone 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
9-Methylstreptimidone
目录号:
HY-134090
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