Cephalosporin C zinc salt  (Synonyms: 头孢菌素C锌盐)

Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC₅₀ of 1.1 μM^[1]. Cephalosporin C zinc salt also has moderate anti-orthopoxvirus activity^[2].

Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC₅₀ of 1.1 ± 0.1 μM, 200-fold more potent than Na⁺ salt form of Cephalosporin C (ICC₅₀^CC-Na = 213 ± 30 μM)^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

478.78

C₁₆H₁₉N₃O₈SZn

59143-60-1

固体

White to off-white

头孢菌素C锌盐

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

• [1]. Seamon KJ, et al. A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase. J Biomol Screen. 2015 Jul;20(6):801-9.  [Content Brief]

  [2]. Donald F Smee, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52.  [Content Brief]