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  3. Amino Acid Derivatives
  4. Fmoc-Thr[GalNAc(Ac)3-α-D]-OH

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH  (Synonyms: Fmoc-Thr(Ac₃AcNH-α-Gal)-OH)

目录号: HY-P0232 纯度: 99.53%
COA 产品使用指南

摩尔计算器

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 是用于研究制备癌症疫苗的结构单元。

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Custom Peptide Synthesis

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH Chemical Structure

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH Chemical Structure

CAS No. : 116783-35-8

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规格 价格 是否有货 数量
1 mg ￥204
In-stock
5 mg ￥478
In-stock
10 mg ￥703
In-stock
25 mg ￥1185
In-stock
50 mg ￥1888
In-stock
100 mg ￥2963
In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Customer Review

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.

体外研究
(In Vitro)

The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA, making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser/Thr (Tn +antigen). This precursor is generated in the Golgi apparatus on newly synthesized glycoproteins by a family of polypeptide α- N-acetylgalactosaminyltransferases (ppGalNAcTs) and then extended to the common core 1 O-glycan Galβ1-3GalNAcα1-OSer/Thr (T antigen) by a single enzyme termed the T-synthase (core 1 β3-galactosyltransferase or C1GalT). Formation of the active form of the T-synthase requires a unique molecular chaperone termed Cosmc, encoded by Cosmc on the X-chromosome[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 相关抗体:
分子量

670.66

Formula

C33H38N2O13
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : ≥ 100 mg/mL (149.11 mM; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.4911 mL 7.4553 mL 14.9107 mL
5 mM 0.2982 mL 1.4911 mL 2.9821 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.53%

COA (297 KB) HNMR (320 KB) LCMS (94 KB)

产品使用指南 (1538 KB)
参考文献

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4911 mL 7.4553 mL 14.9107 mL 37.2767 mL
5 mM 0.2982 mL 1.4911 mL 2.9821 mL 7.4553 mL
10 mM 0.1491 mL 0.7455 mL 1.4911 mL 3.7277 mL
15 mM 0.0994 mL 0.4970 mL 0.9940 mL 2.4851 mL
20 mM 0.0746 mL 0.3728 mL 0.7455 mL 1.8638 mL
25 mM 0.0596 mL 0.2982 mL 0.5964 mL 1.4911 mL
30 mM 0.0497 mL 0.2485 mL 0.4970 mL 1.2426 mL
40 mM 0.0373 mL 0.1864 mL 0.3728 mL 0.9319 mL
50 mM 0.0298 mL 0.1491 mL 0.2982 mL 0.7455 mL
60 mM 0.0249 mL 0.1243 mL 0.2485 mL 0.6213 mL
80 mM 0.0186 mL 0.0932 mL 0.1864 mL 0.4660 mL
100 mM 0.0149 mL 0.0746 mL 0.1491 mL 0.3728 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

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目录号：
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