1. Anti-infection
  2. Bacterial
  3. Nucleocidin

Nucleocidin  (Synonyms: 4'-Fluoro-5'-O-sulfamoyladenosine; NSC 521007)

目录号: HY-100496
产品使用指南

Nucleocidin 是一种抗生素,抑制标签氨基酸从 S-RNA 转运到蛋白质的过程。

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Nucleocidin Chemical Structure

Nucleocidin Chemical Structure

CAS No. : 24751-69-7

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规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nucleocidin is an antitrypanosomal antibiotic, inhibiting the transfer of labeled amino acid from S-RNA to protein.

IC50 & Target

Antibacterial[1].

体外研究
(In Vitro)

Although appreciable inhibition occurrs at low concentrations of nucleocidin, it is not possible to obtain complete inhibition even at 10-3 M. An appreciable lag occurrs before any inhibition by nucleocidin is detectable, and the length of this lag period varies inversely with the concentration of nucleocidin. Similar results are obtained when nucleocidin is added to the cell-free system from reticulocytes. By contrast, essentially complete inhibition is obtained at 10-3 M puromycin, and only at the lowest concentrations is any lag detectable. It seems that nucleocidin exhibits the pattern typical of many antibiotics, i.e. it inhibits incorporation at a stage subsequent to the formation of aminoacyl-S-RNA[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

364.31

Formula

C10H13FN6O6S

CAS 号
中文名称

核杀菌素

结构分类
初始来源

Streptomyces calvus

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
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