2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. Pparδ agonist 1

Pparδ agonist 1 是 PPAR-δ 的激动剂，EC50 值为 5.06 nM，可用于研究与 PPAR-δ 相关的疾病，例如：线粒体疾病、肌肉疾病、血管疾病、脱髓鞘疾病和代谢疾病。

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Pparδ agonist 1 Chemical Structure

Pparδ agonist 1 Chemical Structure

CAS No. : 1902161-12-9

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Pparδ agonist 1 相关抗体

Top Publications Citing Use of Products

查看 PPAR 亚型特异性产品:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pparδ agonist 1 is a PPAR-δ agonist, with an EC50 of 5.06 nM, used in the research of PPAR-delta related diseases, such as mitochondrial diseases, muscular diseases, vascular diseases, demyelinating diseases and metabolic diseases.

IC50 & Target[1]

PPARδ

5.06 nM (EC50)

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CHO-K1 EC50
5.06 nM
Compound: 8a
Transactivation of ProLink tagged human PPARdelta transfected in CHO-K1 cells assessed as interaction with EA labelled SRCP after 3 to 16 hrs by beta galactosidase reporter gene assay
Transactivation of ProLink tagged human PPARdelta transfected in CHO-K1 cells assessed as interaction with EA labelled SRCP after 3 to 16 hrs by beta galactosidase reporter gene assay
[PMID: 27660684]
CV-1 EC50
56 nM
Compound: 8a
Transactivation of human Gal4-PPARdelta LBD transfected in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay
Transactivation of human Gal4-PPARdelta LBD transfected in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay
[PMID: 27660684]
体外研究
(In Vitro)

Pparδ agonist 1 (Compound 8a) is a PPAR-δ agonist, with an EC50 of 5.06 nM, used in the research of PPAR-delta related diseases, such as mitochondrial diseases, muscular diseases, vascular diseases, demyelinating diseases and metabolic diseases[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pparδ agonist 1 相关抗体:
分子量

433.50

Formula

C26H27NO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pparδ agonist 1 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pparδ agonist 11902161-12-9Pparδ agonist1Pparδ agonist-1PPARPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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目录号：
HY-107901
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