2. Membrane Transporter/Ion Channel
  3. Na+/H+ Exchanger (NHE)
  4. Rimeporide hydrochloride

Rimeporide hydrochloride  (Synonyms: EMD-87580 hydrochloride)

目录号: HY-19273A
产品使用指南

摩尔计算器

Rimeporide hydrochloride (EMD-87580 hydrochloride) 是一种有效的选择性 Na+/H+ 交换泵 (NHE-1) 抑制剂。

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Rimeporide hydrochloride Chemical Structure

Rimeporide hydrochloride Chemical Structure

CAS No. : 187870-95-7

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Rimeporide hydrochloride 的其他形式现货产品:

Other Forms of Rimeporide hydrochloride:

Rimeporide hydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).

IC50 & Target

NHE1[1]
体外研究
(In Vitro)

Blocking NHE-1 activity has been shown to decrease intracellular Na+ and Ca2+ overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Rimeporide hydrochloride 相关抗体:
Clinical Trial
分子量

369.84

Formula

C11H16ClN3O5S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Rimeporide hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rimeporide187870-95-7EMD-87580EMD87580EMD 87580Na+/H+ Exchanger (NHE)Sodium/hydrogen ExchangerSodium-hydrogen ExchangerInhibitorinhibitorinhibit

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